Mentor: Ben Evans
Project title: Optimizing heating efficiency of magnetic microspheres for magnetic hyperthermia treatment of malignant tumors
This semester was very important for molding the specific direction of my project. First, I continued my progress from last semester and continued to attempt to control the size of my magnetic nanoparticles. I successfully created two monodisperse samples with sizes that differed by an order of magnitude. With this success, I was able to take measurements of the heating efficiency of each sample and compare the two sizes. Surprisingly, I found that the SAR was not significantly different between the two. This required us to analyze more deeply why this data differed from what the literature showed. After more literature searching, we concluded that the issue was probably a complication with the concentration of each sample.
We discovered from the literature that concentration appears to have a significant effect on heating efficiency, and since we were unable to control for this effect in our samples, we were unable to get accurate data on the effect of size control. With this new knowledge, we decided to move away from size control and investigate of the effect of concentration on heating efficiency. This will allow us not only to get more accurate data, but also to potentially make the largest contribution to the field. The effect of concentration is still debated in current literature, thus this part of the project has the potential to yield noteworthy results for not only my current project but also the future research of others.
Dr. Ann J. Cahill
Professor of Philosophy
Spence Pavilion 111
2340 Campus Box
Elon, NC 27244
Phone: (336) 278-5703
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