Headshot of Jonathan Su

Jonathan Su

Associate Professor of Engineering

Department: Engineering

Office and address: Innovation Hall, Office 105A 2630 Campus Box Elon, NC 27244

Phone number: (336) 278-6934

Brief Biography

Jonathan Su, associate professor of engineering, holds a BS in Mechanical Engineering from Stanford University, a M.Eng. in Mechanical Engineering (Bioengineering certificate) from Cornell University, and a PhD in Mechanical Engineering/Materials Science from Duke University (Center for Biologically Inspired Materials and Material Systems), with additional postdoctoral training in the biomedical engineering department at Northwestern University.   As an expert in mass transport, his research has focused on physical and surface chemistry which examined transport of molecules through surfaces, membranes, and films.  Additionally, he has worked on a variety of topics involving drug delivery for women’s health and HIV prevention, including development of a long-acting implant, vaginal rings, and vaginal fluid simulants.   His research with students has covered an array of topics including development of a pulse oximeter with integrated skin color sensing, mechanical testing of biodegradable implants, holographic imaging for bacterial detection, and preservation and testing of natural dyes.  He also listed as a faculty member in biochemistry. 

News & Notes

Education

Jonathan Su has a BS in Mechanical Engineering from Stanford University, a M.Eng. in Mechanical Engineering (Bioengineering certificate) from Cornell University, and a PhD from Duke University in Mechanical Engineering and Materials Science with a certificate from the Center for Biologically Inspired Materials and Material Systems. 

He completed postdoctoral training at Northwestern Unversity, where he worked on the development of drug delivery systems to prevent the transmission of HIV.

Publications

Dipu Karunakaran, Solange M Simpson, Jonathan T. Su, Ewa Bryndza-Tfaily, Thomas J. Hope, Ronald Veazey, Georgina Dobek, Jiang Qiu, David Watrous, Samuel Sung, Jorge E. Chacon, Patrick F. Kiser., "Design and Testing of a Cabotegravir Implant for HIV Prevention", J. Controlled Release (2021), vol 330, 658 - 668.

Solange M Simpson, Lakmini Widanapathirana, Jonathan T Su, Samuel Sung, David Watrous, Jiang Qiu, Elizabeth Pearson, Alex Evanoff, Dipu Karunakaran, Jorge E Chacon, Patrick F Kiser, "Design of a Drug-Eluting Subcutaneous Implant of the Antiretroviral Tenofovir Alafenamide Fumarate", Pharm Res (2020), vol. 37, 1-16

Jonathan T Su, Solange M Simpson, Samuel Sung, Ewa Bryndza Tfaily, Ronald Veazey, Mark Marzinke, Jiang Qiu, David Watrous, Lakmini Widanapathirana, Elizabeth Pearson, M Melissa Peet, Dipu Karunakaran, Brooke Grasperge, Georgina Dobek, Charlette M Cain, Thomas Hope, Patrick F Kiser, "A subcutaneous implant of tenofovir alafenamide fumarate causes local inflammation and tissue necrosis in rabbits and macaques", Antimicrob Agents and Chemotherapy (2020), vol. 64(3)

 

Kiser, Patrick F.; Clark, Justin; Su, Jonathan T., (2016).  “Drug Delivery to the Female Reproductive Tract”.  In Hillery, Anya; Swarbrick, James; Park, Kinam; “Drug Delivery and Targeting: Fundamentals, Applications and Future Directions”, 2nd Edition, Boca Raton, FL: CRC Press.

Su Jonathan T.; Teller RS; Srinivasan P; Zhang J; Martin A; Sung S; Smith JM; Kiser PF; “A Dose Ranging Pharmacokinetic Evaluation of IQP-0528 Released from Intravaginal Rings in Non-Human Primates”, Pharm Res. (2017), doi 10.007/s 11095-017-2224-1

Taneva E; Crooker K; Park SH; Su, JT; Ott A; Chesen N; Szleifer I; Kiser PF; Frank B; Mesquita PM; Herold, BC; “Differential Mechanisms of Tenofovir and Tenofovir Disoproxil Fumarate Cellular Transport and Implications for Topical Preexposure Prophylaxis”, Antimicrob Agents Chemother. (2015), doi: 10.1128/AAC.02793-15

Rastogi, Rachna*; Su, Jonathan T.*; Mahalingam Alamelu; Clark, Justin; Sung, Samuel; Hope, Thomas; Kiser, Patrick F., “Engineering and Characterization of Simplified Vaginal and Seminal Fluid Simlants”, Contraception, (2015), doi: 10.1016/ j.contraception.2015.11.008. (*Co-first authors)

Aniket; Gaul, David A.; Bitterfield, Deborah L.; Su, Jonathan T.; Li, Victoria M.; Singh, Ishita; Morton, Jackson; Needham, David, “Enzyme Dehydration Using MicroglassificationTM Preserves the Protein’s Structure and Function”, J. Pharm. Sci. (2015) Vol 104 (2), 640-651

Su, Jonathan T.; Needham, David, “Mass Transfer in the Dissolution of a Multi-component liquid droplet in an Immiscible Liquid Environment”, Langmuir, (2013), 29, 13339-13345.

Su, Jonathan T.; Duncan, P. Brent; Momaya, Amit; Jutila, Arimatti; Needham, David, “The effect of hydrogen bonding on the diffusion of water in n-alkanes and n-alcohols measured with a novel single microdroplet method”, J. Chem Physics, (2010) Vol 132 (4): 044506.

Presentations

Su, Jonathan T.; Teller RS; Srinivasan P; Zhang J; Martin A; Sung S; Smith JM; Kiser PF; “A Dose Ranging Pharmacokinetic Evaluation of IQP-0528 Released from Intravaginal Rings in Non-Human Primates”, Controlled Release Society, Boston, MA (2017)

Su, Jonathan T.; Park, Sung-Hyun; Ott, Adina K; Bastian, Rosemary; Maric, Danijela; Hope, Thomas J; Szleifer, Igal; Kiser, Patrick F. “Degradation, transport, and uptake of tenofovir disoproxil fumarate in the female reproductive tract”, Research For Prevention (R4P), Chicago, IL (2016)

Ott, Adina; Halavaty, Katarina K; Su, Jonathan T.; Maric, Danijela; Sung, Samuel; Marzinke, Mark; Hope, Thomas; Kiser, Patrick F. “Transport of Drug and Virus in FRTs of Macaques Treated with a TDF Intravaginal Ring”, Conference on Retroviruses and Opportunistic Infections (CROI), Boston, MA (2016)

Su, Jonathan T.; Sung, Samuel; Kulkarni, Pallavi; Draganoiu, Elena; Kiser, Patrick, “Permeability and Diffusion of Pharmaceuticals through Thermoplastic Polyurethanes”, American Association of Pharmaceutical Sciences, Orlando, FL (2015)

Aniket; Tang, Nicholas; Su, Jonathan T.; Rosenberg, Jordana; Chilkoti, Ashutosh; Needham, David, “Elastin-like Polypeptide Microspheres: A Stimuli-Responsive Vehicle for Controlled Drug Delivery”, Society for Biomaterials, Charlotte, NC (2015)

Su, Jonathan T.; Duncan, P. Brent; Needham, David, “Effect of hydrogen bonding on small solute diffusion explored with the micropipette technique” 6th International Nanomedicine and Drug Delivery Symposium, Toronto, Canada (2008)

Su, Tsu-Te; Su, Jonathan T., “Theory of Vortex Fusion”, Bulletin of the American Physical Society, Division of Fluid Dynamics, Vol. 46, No. 10, Page 102, 2001

Su, Jonathan T. et al, “On N-fold Propellers and Turbines”, Bulletin of the American Physical Society, Division of Fluid Dynamics, Vol. 46, No. 10, Page 130, 2001

Su, Jonathan T. “Use of Neural Networks in Drag Resistance Prediction”, Engineering Mechanics, Proceedings of the 11th Conference, Vol. 2, pp. 1139-1141, 1996.