Biochemistry / Psychology / Math
Project title: Mechanism of neurotoxic α-synuclein oxidation by dopamine in Parkinson’s disease
Mentor: Kathryn Matera
The first thing I accomplished this semester was repeating an experiment I had done in the fall. It was a thioflavin T assay that allowed me to quantify the degree to which norepinephrine inhibited the formation of large protein aggregates. I repeated the experiment because, now that I have the procedure worked out, I wanted to add error bars representing statistical significance to the graph of the data. Next, I spent a majority of the semester running western blot experiments with norepinephrine primary antibodies on oligomer aggregates. This was done to try to figure out how norepinephrine was interacting with the protein to inhibit large fibril formation and accelerate smaller oligomer formation. Since norepinephrine is not a protein, it was difficult to get this procedure to work, and unfortunately I was unable to work out the kinks before the end of the semester. My work was presented orally at NCUR in Lexington, KY and on SURF day. Finally, I spent the last part of the semester taking everything I have accomplished since summer 2012 and putting into a written form.
Dr. Ann J. Cahill
Professor of Philosophy
Spence Pavilion 111
2340 Campus Box
Elon, NC 27244
Phone: (336) 278-5703
Three Elon faculty members and a university Lumen Scholar shared their work at the 2014 American Anthropological Association annual meeting in Washington, D.C.
Senior Thomas Lampl has used the university’s highest honor for undergraduate research and creative achievement to study a laboratory model that may help future doctors better understand the human body’s reaction to sepsis.
Alexander Bruch ’14 sought feedback from chemistry professors & staff in the Student Professional Development Center as he applied to graduate schools, including Yale University, for a doctorate in electrical engineering.
Senior biochemistry majors and Lumen Scholars Taylor Davis and Tom Lampl had a manuscript about their research accepted for publication in the Journal of Visual Experimentation.
Caley Mikesell is one of eight fellows from around the world spending June and July in rural India to help research and develop holistic programs aimed at improving conditions for impoverished villages.
Recent Elon University graduate Sarah Holland's study of Christian complicity in the evils of Nazi Germany shed light on the way people of faith can be led astray by leaders who exploit religious beliefs at the expense of marginalized populations.