Biochemistry / Psychology / Math
Project title: Mechanism of neurotoxic α-synuclein oxidation by dopamine in Parkinson’s disease
Mentor: Kathryn Matera
The first thing I accomplished this semester was repeating an experiment I had done in the fall. It was a thioflavin T assay that allowed me to quantify the degree to which norepinephrine inhibited the formation of large protein aggregates. I repeated the experiment because, now that I have the procedure worked out, I wanted to add error bars representing statistical significance to the graph of the data. Next, I spent a majority of the semester running western blot experiments with norepinephrine primary antibodies on oligomer aggregates. This was done to try to figure out how norepinephrine was interacting with the protein to inhibit large fibril formation and accelerate smaller oligomer formation. Since norepinephrine is not a protein, it was difficult to get this procedure to work, and unfortunately I was unable to work out the kinks before the end of the semester. My work was presented orally at NCUR in Lexington, KY and on SURF day. Finally, I spent the last part of the semester taking everything I have accomplished since summer 2012 and putting into a written form.
Dr. Ann J. Cahill
Professor of Philosophy
Spence Pavilion 111
2340 Campus Box
Elon, NC 27244
Phone: (336) 278-5703
The university's top award comes with $15,000 to support and celebrate academic and creative achievements.
Elon senior Nicole Payne Mota, whose Cuban and Puerto Rican heritage are reflected in her musical passion and scholarly work, led a Yeager Recital Hall concert on April 24 supported by the university's top prize for undergraduate research and creative achievement.
Omolayo Ojo, an international studies major and Honors Fellow from Maryland, will spend a year in Europe before pursuing graduate studies in immigration law, migration and development.
Elon University junior Helen Meskhidze received a scholarship through the national Society of Physics Students.
Mary Rouse, a political science major from Charlotte, North Carolina, will study strategic narratives next year at Royal Holloway, University of London, as she works toward a graduate degree in media, power and public affairs.
Elon University senior Taylor Davis traveled to Boston in March 2015 to present her research at a national biochemistry conference. The Honors Fellow received a student travel award and was recognized in the undergraduate poster competition.